Transitional epithelial cancers in upper urinary tract are quite rare. It is less often being synchronous with the bladder cancer and this situation needs closer follow-up of the patient. In this case report, we evaluated a 56 years-old male having a giant hydronephrosis and nonfunctional kidney, urethra tumor in the light of current literature. The patient presented with right flank pain, palpable abdominal mass and intermittent hematuria in last one years.
Keywords: Giant hydronephrosis and nonfunctional kidney, urethra tumor, transitional epithelial cancer