Inflammatory cells can be seen in most of the surgical specimens of BPH. Activated T cels are the major source of cytokines. Chronic inflammation also induces progression of the BPH symptoms and acute retention. Clinical studies showed that inflammation is associated with prostate size and age of the patient Because of this relation anti-inflammatory drugs has tested in the treatment of BPH with a short clinical response.From all these studies we can say that chronic inflammation is a risk factor for BPH and related symptoms.