Objective:

In this study it was aimed to evaluate development of intra-operative Floppy Iris syndrome (FIS) and related complications in a patient receiving tamsulosin or doxazosin and underwent phacoemulsification surgery for cataract.

Materials and Methods:

Data of patients underwent phacoemulsification surgery at Sorgun State hospital between November 2011 and May 2013 was reviewed retrospectively. Patients were investigated in 3 groups, as prescribed tamsulosin, doksazosin or control group. Rate of IFIS development and related complications were compared.

Results:

Totally 211 eyes of 167 patients were operated. In the tamsulosin group 31 eyes of 23 patients, in the doxazosin group 20 eyes of 16 patients and in the control group 160 eyes of 128 patients were operated. IFIS developed in 17 eyes (54.8%) in the tamsulosin group, in 4 eyes (20%) in the doxazosin group and in one eye (0.0625%) in the control group. The difference was statistically significant. Totally, complication development was observed in 6 patients (20.8%) and 4 of these patients were in the IFIS developing group (4/22), 2 complications were observed in patients without IFIS (2/189). The difference was statistically significant (p=0.0012).

Conclusion:

Use of tamsulosin significantly increases the risk of development of IFIS and related complications. Patients should be questioned about the use of alpha receptor blockers prior to cataract surgery.

Keywords: Tamsulosin, doxazosin, lower urinary tract symptoms, cataract, Floppy Iris syndrome