ABSTRACT

Renal cell carcinoma is a very heterogeneous disease with widely varying prognosis. Prognosis of RCC is depending upon stage, Fuhrmann grade of tumor and patient's performance status. The size of tumor also very important. But unfortunately many renal masses remain asymptomatic and non palpable until the late stages of the disease. Currently, most RCCs are detected incidentally by the frequent use of imaging modalities for a variety of unrelated symptoms or disease. Therefore it is necessary to screen the population especially in risk groups (People with familial history, hereditary kidney disease, smokers, hypertensive and obese people etc.). There is increasing knowledge on prognostic factors of localized and metastatic RCC.Several predictive models have been developed by combining different prognostic features which are valuable tools for patient counseling. Although there are many nomograms, scores (UISS, Mayo, Leibovitch etc.) to predict the prognosis and survival rates, we do not have any screening tools. The proposal is that imaging techniques in some period of time may be useful for early diagnosis and inform the people especially in risk groups.