ABSTRACT

Neuroendocrine prostate cancer is very rare disease with high mortality. It is one of the most commonly observed extrapulmonary small cell lung cancer types. In this case report we wanted to indicate how aggressive can neuroendocrine carcinoma of the prostate be by presenting a 50-year-old male patient whose liver and bone metastasis progressed in a short period like 6 months although his prostate specific antigen levels were low and he had benign prostatic hyperplasia related symptoms. The definitive diagnosis can be made as a result of pathologic specimen examination by specific dyes. To predict the diagnosis clinically is often thought to be impossible.